New laboratory guidelines for serologic diagnosis of Lyme disease: evaluation of the two-test protocol

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Laboratory evaluation in the diagnosis of Lyme disease.

PURPOSE To provide a qualitative evaluation of the predictive value of the laboratory diagnosis of Lyme disease and to use the resultant data to formulate guidelines for clinical diagnosis. DATA SOURCES A MEDLINE search of English-language articles or articles with English-language abstracts published from 1982 to 1996. DATA EXTRACTION Sensitivity, specificity, and likelihood ratios were ca...

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Clinical evaluation of guidelines and two-test approach for lyme disease.

OBJECTIVE The diagnosis of Lyme disease should be based on objective clinical signs and symptoms. In a clinical study, we have evaluated whether the recommended two-step approach for serodiagnosis of Lyme disease is useful in daily clinical practice and can influence clinical decision making. METHODS The signs and symptoms of patients with ongoing musculoskeletal complaints, assumed by their ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1996

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.34.10.2343-2350.1996